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New antibiotic could curb hearing loss

Published

9 years ago

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New York: A new version of a common antibiotic could eliminate the side effects associated with the drug – risk of hearing loss and kidney damage, a new research has found.

Treatment with aminoglycosides, the most commonly used class of antibiotics worldwide, is often a lifesaving necessity.

But an estimated 20-60 percent of all patients who receive aminoglycosides, which is also used in treatment of cancer, suffer partial or complete hearing loss.

The newly patented antibiotic, N1MS, which is derived from sisomicin, a type of aminoglycoside, works effectively in mice without the risk of causing deafness or kidney damage, the researchers found.

“Our goal is to replace the existing aminoglycosides with ones that are not toxic,” said co-senior author of the study Anthony Ricci, professor at Stanford University School of Medicine.

The researchers said they hope to test the modified antibiotic in humans as soon as possible.

“If we can eventually prevent people from going deaf from taking these antibiotics, in my mind, we would have been successful,” Ricci said.

The study found that N1MS cured urinary tract infection in mice just as well as sisomcicin but did not cause deafness.

Unlike the parent compound, N1MS was non toxic to the kidneys too, the results showed.

The study presents a promising new approach to generating a new class of novel, non toxic antibiotics, Ricci pointed out.

“We targeted sites on the drug molecule that were not involved in the antimicrobial activity that kills off infection. This allowed us to reduce toxicity to the ear while retaining antimicrobial action,” Ricci said.

The study appeared in the Journal of Clinical Investigation.

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Health

These three drinks can be a blessing for your gas and acidity problems

Published

2 years ago

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April 17, 2022

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ily foods, spicy dishes, fried fares… Done it all and regretting it? If you’re suffering from acid reflux, you probably know what to eat and what to avoid. But is there anything to relieve you from such digestive issues? Well, there are certain drinks for acidity to improve your digestive health, if you consume them regularly.

Ready to find out? Let’s go!

In an Instagram video, nutritionist and health coach Neha Ranglani has suggested that to calm your acid reflux, you need to help your food get digested well. This can be done by improving your stomach acid production and healing your stomach cells. And these drinks that she has suggested, can help with just that, allowing you to digest your food well without the burn.

Here are 6 drinks for acidity:

1. Cucumber juice

Cucumber is a favourite salad ingredient in summer because of its cooling properties. Consuming cucumber juice can be really beneficial for relievingacid reflux because it is highly nutritious as it provides your body with both fibre and water which is needed for better digestion and has a low calorie volume. What’s more? It can also keep you full and help you avoid reaching out to junk foods!

2. Lemon water

Lemon can do you a world of good! Being rich in vitamin C and B and minerals such as phosphorus, calcium, and magnesium—drinking lemon water regularly will not only help you burn fat but will resolve your digestive issues such as acidity. Moreover, lemon water contains laxative properties that can help improve your bowel movements and clear toxins from the body, keeping you hydrated.

3. Ginger water

Ginger aka adrak, is a very well known ingredient that has been used for ages to help relieve acidity and gas. Also, if you are facing digestive issues due to overeating or undigested food, consuming ginger water can help in emptying your stomach. You can also consume it by adding it to soups, subzi or curry, and even tea. Remember that you’re not allowed to consume ginger in excess amounts.

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