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BP pills before sleep lower diabetes risk too

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London: Taking blood pressure pills at bedtime rather than in the morning not only reduces BP while asleep but also lowers the risk of developing Type 2 diabetes, promising research has revealed.

The team of Spanish researchers found that there was a 57 percent decrease in the risk of developing new-onset Type 2 diabetes in the bedtime-treated group.

“In hypertensive patients without diabetes, ingestion of the entire daily dose of one or more blood pressure-lowering medications at bedtime results in significantly improved sleeping blood pressure control and prevention of new-onset diabetes,” said Ramon Hermida from University of Vigo, Spain.

The team did a randomised trial of 2,012 hypertensive patients without diabetes (976 men and 1,036 women).

Patients were randomised to ingest all their prescribed hypertension medications upon awakening or the entire daily dose of one or more of them at bedtime.

Investigators who did not know which patients were in which group assessed the development of new-onset diabetes.

During a median follow-up of six years, 171 participants developed Type 2 diabetes.

Patients in the bedtime — compared with the morning-treatment group — showed a significantly lower asleep mean BP and a greater sleep-time relative BP decline.

In the bedtime-treated group, there was a lower-prevalence of a phenomenon known as “non-dipping” in which, patients’ night time BP falls by less than 10 percent compared to daytime BP.

Further analysis showed that greater reduction in risk of developing diabetes was observed for bedtime compared with awakening treatment.

The authors conclude that before bed regimen of taking anti-hypertensive medications is as safe as taking them in the morning.

The research was published in Diabetologia – the journal of the European Association for the Study of Diabetes.

Corona

Covid toll in Karnataka is a worrying sign for state government

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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