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Brucellosis another disease spred in China make men infertility.



The world is already battling a pandemic, And we have an another big disease outbreak in China.

The health commission of Lanzhou City in China announced an outbreak of brucellosis disease which was caused due to a leak in a biopharmaceutical company last year.

What is Brucellosis?

Brucellosis is a bacterial disease that mostly infects cattle, swine, goats, sheep and dogs. Humans can get infected by this disease by being in direct contact with these livestock animals. There can also be a human to human transmission of this infection if a person eats the infected food.

The impact of the spread:

This disease has infected over 3,000 people in China so far. 3265 in the North West of China have tested positive for the bacterial disease, Brucellosis, aka Mediterranean fever.

What are the symptoms of the disease:

Symptoms of this disease include fever, sweats, malaise, anorexia, headache and muscle pain. There are some symptoms that might eventually disappear, but some can also stay forever such as recurrent fevers, arthritis, swelling of the testicles and scrotum area, swelling of the heart.

But what’s concerning is. In rare cases, this disease can also serious symptoms such as infertility in men.

When did the outbreak happen:

The leak took place in a biopharmaceutical company named Zhongmu Lanzhou, last year, between the month of July and August while producing veterinary vaccinations for this disease.

How did the outbreak happen:

Outdated disinfectants and sanitizers were used during the production of Brucella vaccines for animal use. This caused the waste gas to leak from the factory which contained this bacteria.


Study reveals kidney disease or injury is associated with much higher risk of mortality for COVID-19 patients



Researchers, including one of Indian-origin, have found that there is much higher risk of mortality faced by COVID-19 patients in intensive care, who have chronic kidney disease (CKD), or those who develop new (acute) kidney injury (AKI).

CKD is a type of kidney disease in which kidney function declines over a period of months to years, and is more common in older people.

AKI is an abrupt loss of kidney function that takes place over seven days or less and can have several causes, including the damage and inflammation caused by the COVID-19 virus itself.

“To the best of our knowledge, this is the first comprehensive analysis of outcomes in critically unwell COVID-19 patients in the UK with kidney failure, particularly in patients with pre-existing chronic kidney disease,” said study author Sanooj Soni from Imperial College London in the UK.

For the study, published in the journal Anaesthesia, the research team examined the association between AKI and CKD with clinical outcomes in 372 patients with COVID-19 admitted to four regional intensive care units (ICUs) in the UK.

The average age of the patients was around 60 years, and 72 percent of them were male.

A total of 216 (58 percent) patients had some form of kidney impairment (45 percent developed AKI during their ICU stay, while 13 percent had pre-existing CKD), while 42 percent had no CKD or AKI.

The patients who developed AKI had no history of serious kidney disease before their ICU admission, suggesting that the AKI was directly related to their COVID-19 infection.

The authors found that patients with no kidney injury or disease had a mortality of 21 percent.

Those with new-onset AKI caused by the COVID-19 virus had a mortality of 48 percent, whilst for those with pre-existing CKD (Stages 1-4) mortality was 50 percent.

In those patients with end-stage kidney failure (CKD stage 5), where they already required regular out-patient dialysis, mortality was 47 percent.

Mortality was greatest in those patients with kidney transplants, with six out of seven patients (86 percent) dying, highlighting that these patients are an extremely vulnerable group.

The investigators also examined the rates of renal replacement therapy, a form of hospital dialysis, due to COVID-19 in these ICU patients with kidney injury.

Out of 216 patients with any form of kidney impairment, 56 per cent of patients requiring renal replacement therapy, the researchers said.

The authors noted that mortality in patients with end-stage kidney failure and on dialysis, who normally have worse outcomes in many other diseases, was similar to that in patients with less severe kidney disease and Covid-19 associated AKI.

This finding may suggest that such patients benefit equally from ICU admission and thus the threshold for admission should be calibrated accordingly in any future COVID-19 surge.

“Our data demonstrate that kidney disease and failure in critically ill patients with COVID-19 are common, and associated with high mortality,” the authors noted.

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