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To prepare special strategy for COVID control in Lucknow, Kanpur, Meerut directs CM Yogi.

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In Uttar Pradesh, Chief Minister Yogi Adityanath has directed to prepare a special strategy for COVID control in Lucknow, Kanpur city and Meerut districts.

These districts have seen the surge in the number of new COVID cases recently.

The Chief Minister said that the state has been able to control the spread of the pandemic to a great extent.

This is a good sign that the number of active cases has come down during the last one week. It clearly shows that the strategy with regards to Corona control has been effective.

The strategy of UP Government for curbing the spread of infection is providing positive results now.

Despite having the highest number of COVID tests per day in the country which is more than 1. 5 lakh per day positivity rate is coming down and the recovery rate has reached 84.75 per cent.

From 18th of this month, the number of new COVID cases is less than the patients recovered per day.

On Monday also 3,838 new active cases were found in the state and 5,382 patients were discharged after full recovery.

The Chief Minister has appointed special officers in those 16 districts which have more than 100 new cases per day.

One Principal Secretary, one Special Secretary, one health specialist and one medical education expert is camping in these districts.

State currently has 53,953 active COVID patients and with 60 new deaths the toll of deaths due to the deadly virus has reached 5,652.

Corona

Call for Covid-19 studies to focus on mucosal immunity

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Researchers have stressed that more Covid-19 studies should be devoted to how immunity to coronavirus emerges in the mucous membranes of the nose and mouth.

Anyone who has undergone a nasal swab or saliva test for Covid-19 knows that the virus is most easily detected in the nose and mouth, the study, published in the journal Frontiers in Immunology, reported.

Noting that the mucosal immune system is the immune system’s largest component, the researchers expressed concern that it hasn’t been a focus of much of the research on Covid-19 to date.

“We think it is a serious omission to ignore the mucosal immune response to SARS-CoV-2, given its initial sites of infection,” said study author Michael W Russell from the University at Buffalo in the US.

“Clearly the response of the systemic immunoglobulin G antibody (the most abundant circulating antibody) is important — we do not deny that — but on its own it is insufficient,” Russell added.

Russell noted that naturally, the initial focus of research on the disease was on cases of severe disease when the virus descends into the lower respiratory tract, especially the lungs, where the cellular immune responses exacerbate the inflammation rather than fight the infection.

But since the upper respiratory tract, including the nose, tonsils and adenoids are the initial point of infection for the SARS-CoV-2 virus, the immune responses that are triggered there are of special interest.

“Given that many infected people remain asymptomatic, and that a large number of those who develop symptoms suffer only mild to moderate disease, this suggests that something, somewhere, does a fairly good job of controlling the virus,” said Russell.

“Could it be that this is due to early mucosal immune responses that succeed in containing and eliminating the infection before it becomes serious? We will not know unless these questions are addressed,” he asked.

The paper recommends that studies are needed to determine the nature of mucosal secretory immunoglobulin A (SIgA) antibody responses over the course of infection, including asymptomatic or pre-symptomatic infection, and mild and moderate cases of Covid-19 disease.

In addition, the authors point out that the mucosal immune responses may vary depending on different age groups and populations.

 

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