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China coronavirus toll reaches 908, 40,171 infected

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Beijing: The death toll due to the novel coronavirus in China on Monday increased to 908, with 40,171 confirmed cases, the country’s National Health Commission said.

Until midnight, 6,484 severe cases had been recorded while 3,281 people, who had recovered from the illness, had been discharged, Efe news reported citing the Commission as saying.

As of now, 399,487 patients in close contact with the infected have been traced, out of which 187,518 are under observation, according to the Chinese agency.

Among those under observation, 23,589 were suspected of having contracted the virus.

The latest figures indicate an increase of 97 deaths over the previous day – when 632 people were also discharged – and 3,062 new infections.

Of the 97 deaths, 91 were recorded in Hubei province, whose capital is Wuhan – the epicentre of the outbreak -, and which has been under de facto quarantine since January 23.

It total, 2,618 of the 3,062 new coronavirus cases have been detected in Hubei.

Until now, all deaths but one – which occurred in the Philippines – have been in China, which accounts for about 99 per cent of those infected, although about 20 countries have confirmed cases.

The virus has already claimed more lives than the Severe Acute Respiratory Syndrome (SARS) in 2003.

Despite both the novel coronavirus and SARS originating in China, the geographical distribution of deaths is radically different.

SARS emerged in the southern Guangzhou province, while the coronavirus appears to have originated from a seafood market in the central-eastern city of Wuhan.

With SARS, 349 people died in mainland China, 299 in Hong Kong, 43 in Canada, 37 in Taiwan and 33 in Singapore, to mention only the most affected places, according to the figures from WHO.

Coronavirus has spread to at least 27 other countries and territories.

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Rare genetic brain disease reported, ‘Myoclonus-Dystonia’

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Bangalore: A rare genetic brain disease causing a movement disorder has been reported from Mumbai where a 21-year-old patient has been diagnosed with ‘Myoclonus-Dystonia’ with facial, neck and hand shaking and jerking due to rare genetic disorder called ADCY5-related dyskinesia.

This is a rare disease with less than 400 cases reported all over the world. The disorder is known to cause abnormal involuntary tremors in the body and is usually seen in children, but this is the first time it has been reported in an Indian adult patient.

He suffered from the condition since he was 13, but these jerks were initially mild. This progressed to moderate severity over the last few years. “We were able to manage the trembling till the time they were mild. With time, the intensity increased and so did the frequency which hampered daily activities and even any work that needed concentration”, told the parents of the 21 year old.

Dr VL Ramprasad, COO, MedGenome Labs that performed the genetic testing said, “ADCY5 mutation causes abnormal involuntary movements affecting the neck, arms and face. This mutation can also lead to episodic worsening triggered by anxiety, stress or inactivity -or characteristically periods before or after sleep. We have now published this case in MDCP (Movement Disorders Clinical Practice), which is a well-known journal.”

The doctor informed that when the patient came to them he would get these movements in spells intermittently in the early years. His whole body was shaking when he was anxious or even concentrating on an activity. After initial tests the doctors were convinced that he had a rare genetic disorder and tests confirmed ADCY5 gene mutation

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