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Deadly sleeping sickness can also be spread via skin

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sleeping sickness, skin ,Deadly, London, Human African Trypanosomiasis, Africa,health,London: Skin plays a significant role in harbouring and transmitting trypanosomes — the parasite that causes the Human African Trypanosomiasis, more commonly known as African sleeping sickness, which is often fatal if left untreated, a new research has found.

The findings could have a major impact on the way the disease is diagnosed, treated and potentially eradicated. The disease, which kills thousands in Sub-Saharan Africa every year, is primarily transmitted to humans via the bite of an infected tsetse fly as it takes a blood meal, with diagnosis then confirmed through the presence of parasites in the blood.

The current study, published recently in the journal e-Life, showed that substantial quantities of trypanosomes that cause the disease can exist within the skin and can be transmitted back to the tsetse fly vector.

“Our results have important implications with regard to the eradication of sleeping sickness. Firstly, our findings indicate that current diagnostic methods, which rely on observing parasites in the blood, should be re-evaluated and should include examining the skin for parasites,” said lead researcher Annette MacLeod from University of Glasgow in Britain.”In terms of treatment, it may also be necessary to develop novel therapeutics capable of targeting sources of infection outside the blood circulation and in the reservoirs underneath the skin,” MacLeod noted.

The team of researchers from University of Glasgow’s Wellcome Trust Centre for Molecular Parasitology and the Institut Pasteur in Paris were also able to observe the presence of parasites in human skin biopsies from individuals who displayed no symptoms.  The study’s findings suggest skin-dwelling parasites could be sufficiently abundant in the skin to be ingested, transmitted and so able to spread the disease further.

Corona

Covid toll in Karnataka is a worrying sign for state government

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Even though Karnataka recorded the lowest number of Covid deaths in April since the virus struck first in 2020, the state is recording a rise in the positivity rate (1.50 per cent). Five people died from the Covid infections in April as per the statistics released by the state health department. In March, the positivity rate stood around 0.53 per cent. In the first week of April it came down to 0.38 per cent, second week registered 0.56 per cent, third week it rose to 0.79 per cent and by end of April the Covid positivity rate touched 1.19 per cent.

on an average 500 persons used to succumb everyday in the peak of Covid infection, as per the data. Health experts said that the mutated Coronavirus is losing its fierce characteristics as vaccination, better treatment facilities and awareness among the people have contributed to the lesser number of Covid deaths.

During the 4th and 6th of April two deaths were reported in Bengaluru, one in Gadag district on April 8, two deaths were reported from Belagavi and Vijayapura on April 30. The first Covid case was reported in the state in March 2020 and three Covid deaths were recorded in the month. In the following month 21 people became victims to the deadly virus, and May 2020 recorded 22 deaths. The death toll recorded everyday after May crossed three digits. However, the third wave, which started in January 2

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